{"id":23109,"date":"2025-06-10T16:56:32","date_gmt":"2025-06-10T14:56:32","guid":{"rendered":"https:\/\/www.lites.tf.fau.de\/?p=23109"},"modified":"2025-06-16T09:55:30","modified_gmt":"2025-06-16T07:55:30","slug":"growth-trajectories-of-spions","status":"publish","type":"post","link":"https:\/\/www.lites.tf.fau.de\/en\/2025\/06\/10\/growth-trajectories-of-spions\/","title":{"rendered":"(FP\/MA) Growth trajectories of superparamagnetic nanoparticles(SPIONs): From single iron core to chain-like agglomeration"},"content":{"rendered":"<h3>This work is very suitable as FP. Also possible topics for MA have been marked separately.<\/h3>\n<h3>Description<\/h3>\n<p><span class=\"fontstyle0\">Superparamagnetic<\/span><span class=\"fontstyle1\"> iron-oxide nanoparticles <\/span><span class=\"fontstyle1\">(SPIONs), composed of a magnetic iron-oxide core and a tunable non-magnetic coating, exhibit rapid magnetic response along with exceptional stability and biocompatibility [1], [2]. These characteristics have fostered their applications in diverse medical fields including drug delivery [3], diagnostic imaging [4], and hyperthermia therapy [5].<\/span><br \/>\nThe <span class=\"fontstyle1\">characteristics<\/span> of nanoparticles are closely related to their structure. Their structure is well layered. Crystals, iron oxide nuclei, aggregates, clusters and agglomeration are gradually formed as the scale increases. The formation of these different hierarchical structures determines the macroscopic properties of the final nanoparticle.<\/p>\n<h3>Research Questions<\/h3>\n<ul>\n<li>What are the key factors that determine the formation of the corresponding structures at different scales\uff1f<\/li>\n<li>What are the length scales of the different levels of structure? How is this length scale affected?<\/li>\n<li>What are the specific mechanisms by which structures between different scales are transformed?<\/li>\n<\/ul>\n<h3>Research Goals<\/h3>\n<p>Our aim is to clearly explain the structural composition of magnetic nanoparticles across hierarchical levels and their corresponding length scales (FP, MA).<\/p>\n<p>As well as to quantitatively study and visualize the nanoparticle structural composition using molecular dynamics simulations (MA).<\/p>\n<h3>Arbeitspakete<\/h3>\n<ul>\n<li>Literature research on synthesis methods of magnetic nanoparticles, nanoparticle interactions, and structural hierarchy (FP, MA)<\/li>\n<li>Rational visualization of the structural hierarchy of magnetic nanoparticles (FP, MA)<\/li>\n<li>Perform molecular dynamics simulations to model the formation of hierarchical structures (MA)<\/li>\n<\/ul>\n<p>We would very much welcome your questions and comments and will modify the topic accordingly to suit your interests.<\/p>\n<h3>Deine Kenntnisse<\/h3>\n<ul>\n<li>Strong interest in medical technology<\/li>\n<li>Good information gathering skills<\/li>\n<li>Solid knowledge of physics and math<\/li>\n<li>Proficiency in Python and matlab<\/li>\n<\/ul>\n<h3>Literaturangaben<\/h3>\n<ol>\n<li><span class=\"fontstyle0\">S. Laurent, D. Forge, M. Port, A. Roch, C. Robic, L. Vander Elst,<\/span><span class=\"fontstyle0\">and R. N. Muller, \u201cMagnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications,\u201d <\/span><span class=\"fontstyle2\">Chemical Reviews<\/span><span class=\"fontstyle0\">, vol. 108, no. 6, pp. 2064\u20132110, 2008.<\/span><\/li>\n<li><span class=\"fontstyle0\">M. Wu, D. Zhang, Y. Zeng, L. Wu, X. Liu, and J. Liu, \u201cNanocluster of<\/span><span class=\"fontstyle0\">superparamagnetic iron oxide nanoparticles coated with poly (dopamine) for magnetic field-targeting, highly sensitive MRI and photothermal cancer therapy,\u201d <\/span><span class=\"fontstyle2\">Nanotechnology<\/span><span class=\"fontstyle0\">, vol. 26, no. 11, p. 115102, 2015.<\/span><\/li>\n<li><span class=\"fontstyle0\">A. S. Thalmayer, S. Zeising, G. Fischer, and J. Kirchner, \u201cSteering<\/span><span class=\"fontstyle0\">magnetic nanoparticles by utilizing an adjustable linear Halbach array,\u201d in <\/span><span class=\"fontstyle2\">2021 Kleinheubach Conference<\/span><span class=\"fontstyle0\">, pp. 1\u20134, Miltenberg, 2021.<\/span><\/li>\n<li><span class=\"fontstyle0\">H. Unterweger, L. Dezsi, J. Matuszak, C. Janko, M. Poettler, J. Jordan, \u00b4 T. Bauerle, J. Szebeni, T. Fey, A. R. Boccaccini, \u00a8 <\/span><span class=\"fontstyle2\">et al.<\/span><span class=\"fontstyle0\">, \u201cDextrancoated superparamagnetic iron oxide nanoparticles for magnetic resonance imaging: Evaluation of size-dependent imaging properties, storage stability and safety,\u201d <\/span><span class=\"fontstyle2\">International Journal of Nanomedicine<\/span><span class=\"fontstyle0\">, pp. 1899\u2013 1915, 2018.<\/span><\/li>\n<li><span class=\"fontstyle0\">A. Hajalilou, L. Ferreira, M. M. Jorge, C. Reis, and M. Cruz, \u201cSuperparamagnetic Ag-Fe3O4 composites nanoparticles for magnetic fluid hyperthermia,\u201d <\/span><span class=\"fontstyle2\">Journal of Magnetism and Magnetic Materials<\/span><span class=\"fontstyle0\">, vol. 537, p. 168242, 2021<\/span><\/li>\n<\/ol>\n<hr \/>\n<p><div class=\"fau-person person-card\">Es konnte kein Kontakteintrag mit der angegebenen ID 12345 gefunden werden.<\/div><br \/>\n<div class=\"elements-divider\"><\/div><\/p>\n<p style=\"text-align: right\"><a class=\"rrze-elements standard-btn primary-btn\" href=\"mailto:vorname.nachnameg@fau.de?subject=Anfrage%20f\u00fcr:%20FP%20-%20Das%20Leben%20ist%20sch\u00f6n\"><span>Anfrage senden<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>This work is very suitable as FP. Also possible topics for MA have been marked separately. Description Superparamagnetic iron-oxide nanoparticles (SPIONs), composed of a magnetic iron-oxide core and a tunable non-magnetic coating, exhibit rapid magnetic response along with exceptional stability and biocompatibility [1], [2]. These characteristics have fostered their applications in diverse medical fields including [&hellip;]<\/p>\n","protected":false},"author":5063,"featured_media":22033,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_rrze_cache":"enabled","_rrze_multilang_single_locale":"en_US","_rrze_multilang_single_source":"https:\/\/www.lites.tf.fau.de\/?p=23078","footnotes":""},"categories":[581,226],"tags":[612],"workflow_usergroup":[],"class_list":["post-23109","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-fp_eng","category-offene_stud_arbeiten_eng","tag-xiao","en-US"],"_links":{"self":[{"href":"https:\/\/www.lites.tf.fau.de\/wp-json\/wp\/v2\/posts\/23109","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lites.tf.fau.de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lites.tf.fau.de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lites.tf.fau.de\/wp-json\/wp\/v2\/users\/5063"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lites.tf.fau.de\/wp-json\/wp\/v2\/comments?post=23109"}],"version-history":[{"count":2,"href":"https:\/\/www.lites.tf.fau.de\/wp-json\/wp\/v2\/posts\/23109\/revisions"}],"predecessor-version":[{"id":23113,"href":"https:\/\/www.lites.tf.fau.de\/wp-json\/wp\/v2\/posts\/23109\/revisions\/23113"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.lites.tf.fau.de\/wp-json\/wp\/v2\/media\/22033"}],"wp:attachment":[{"href":"https:\/\/www.lites.tf.fau.de\/wp-json\/wp\/v2\/media?parent=23109"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lites.tf.fau.de\/wp-json\/wp\/v2\/categories?post=23109"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lites.tf.fau.de\/wp-json\/wp\/v2\/tags?post=23109"},{"taxonomy":"workflow_usergroup","embeddable":true,"href":"https:\/\/www.lites.tf.fau.de\/wp-json\/wp\/v2\/workflow_usergroup?post=23109"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}